Sunday, January 05, 2025

I Asked A.I.'s ChatGPT about Light Therapy To Safely Remove Large Blood Clots

 


Like many, it is clear a result of covid, either the condition or a result of the vaccination demands radical healing strategies to dissolve clots into pieces small enough to safely pass through the body.


So I asked about Light Therapy to Chat GPT

Light therapies as a blood clot treatment strategy - I found this paper on line https://pmc.ncbi.nlm.nih.gov/articles/PMC7775081/ - Can light therapies help dissolve large blood clots safely and if so which ones should be considered?

ChatGPT

The study you referenced explores light therapies and their potential to address vascular conditions. Light therapies like photobiomodulation (PBM) have been investigated for their ability to enhance blood flow, reduce inflammation, and support tissue repair. These therapies use specific wavelengths of light, usually in the red and near-infrared spectrum, to stimulate cellular processes.

Can Light Therapies Dissolve Large Blood Clots?

Light therapies are not yet established as a primary treatment for dissolving large blood clots (e.g., deep vein thrombosis or pulmonary embolism). However, they might indirectly assist in managing clot-related issues by:

Improving Blood Flow: PBM can stimulate nitric oxide release, a molecule that relaxes blood vessels and improves circulation, potentially reducing clot formation risk.

Reducing Inflammation: By calming inflammatory processes, PBM may create a more favorable environment for natural clot resolution.

Enhancing Fibrinolysis: Some studies suggest light therapy might promote the body's natural ability to break down clots, although this is primarily demonstrated in preclinical settings.

Safety Considerations

While light therapies are generally non-invasive and safe, their use for treating large blood clots specifically has not been sufficiently validated in clinical settings. Large clots often require immediate intervention through anticoagulants, thrombolytics, or mechanical removal.

Promising Light-Based Modalities

Photobiomodulation (PBM): Utilizes low-level lasers or LEDs, typically in the 600-1100 nm range.

Endovenous Laser Therapy (EVLT): For varicose veins, EVLT indirectly affects clot-prone areas, though not designed for dissolving clots.

Pulsed Ultraviolet (UV) Light: Under exploration for microbial sterilization and possibly influencing blood properties.

Blue Light Therapy: Demonstrated antibacterial properties and might support circulation but is less effective for deep tissue.

Recommendations for Consideration

Consult a Specialist: Large clots are life-threatening and require urgent medical advice.

Adjunctive Role: Light therapies could be explored as complementary to standard treatments in managing chronic vascular conditions or post-thrombotic syndrome.

Research Ongoing: Follow emerging clinical studies to stay informed on validated therapeutic uses.

Next Steps

If you’re interested in discussing this topic further, it may be worth connecting with researchers in vascular medicine or photomedicine who can offer expert perspectives on the potential integration of light therapies into clot management strategies.

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I said:

can you please recommend some "researchers in vascular medicine or photomedicine" - I will be incorporating their work into the blog entry on the subject - working title 'How light therapy can help safely break up large blood clots.'

ChatGPT:

Incorporating insights from leading researchers in vascular medicine and photomedicine can enhance your blog entry on how light therapy may aid in safely breaking up large blood clots. Here are some notable experts whose work aligns with your topic:

1. Dr. Jeffrey Kline and Dr. Nathan Alves

Researchers at Indiana University School of Medicine, Dr. Kline and Dr. Alves are exploring nanoparticle technology to develop innovative treatments for blood clots. Their work focuses on creating targeted therapies that can effectively dissolve clots with minimal side effects. 

INDIANA UNIVERSITY'S SCHOOL OF MEDICINE

2. Dr. Gautam Sikka

Dr. Sikka, along with his mentor Dr. Dan Berkowitz at Johns Hopkins University, has conducted research on photorelaxation—the relaxation of blood vessels in response to light. Their studies suggest that light-sensing receptors in blood vessels can mediate wavelength-specific, light-dependent vascular relaxation, potentially offering new avenues for light-based therapies in cardiovascular diseases. 

WIKIPEDIA

3. Dr. Heidi Hamm and Dr. Jens Meiler

Part of a team at Vanderbilt University, Dr. Hamm and Dr. Meiler have developed new drug candidates targeting receptors involved in blood clot formation. Their research utilizes computer-aided drug design to create therapies that could complement light-based treatments in managing blood clots. 

VANDERBILT UNIVERSITY SCHOOL OF MEDICINE

4. Dr. Evangelos Gragoudas and Dr. Joan Miller

Ophthalmologists at Massachusetts Eye and Ear, Dr. Gragoudas and Dr. Miller have been instrumental in developing photodynamic therapy (PDT) with verteporfin (Visudyne) for treating choroidal neovascularization. While their work primarily focuses on eye diseases, the principles of PDT could have broader applications in vascular treatments. 

WIKIPEDIA

5. Dr. Yubing Xie

A researcher at Worcester Polytechnic Institute, Dr. Xie is developing real-time imaging technology to enhance the precision of stroke treatments. Her work involves creating fiber-optic probes that can be guided through catheters to blood clots in the brain, potentially improving the safety and efficacy of clot removal procedures. 

WORCESTER POLYTECHNIC INSTITUTE

Incorporating the research and perspectives of these experts can provide a comprehensive overview of the current advancements in light-based therapies for blood clot treatment. Their work highlights the potential of combining photomedicine with innovative technologies to develop safer and more effective treatments for vascular conditions.



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